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Evidence for central sensitization in chronic whiplash: a systematic literature review. Eur J Pain.
Epub Sep Sterling M, Kenardy J. Physical and psychological aspects of whiplash: Important considerations for primary care assessment. Man Ther.
Epub Jan Pain neurophysiology education improves cognitions, pain thresholds, and movement performance in people with chronic whiplash: a pilot study. J Rehabil Res Dev. Nijs J, Ickmans K. Chronic whiplash-associated disorders: to exercise or not? Efficacy of a modern neuroscience approach versus usual care evidence-based physiotherapy on pain, disability and brain characteristics in chronic spinal pain patients: protocol of a randomized clinical trial.
BMC Musculoskelet Disord.
- Pain | Iowa Neuroscience Institute.
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Moseley L. Combined physiotherapy and education is efficacious for chronic low back pain. Aust J Physiother. The efficacy of patient education in whiplash associated disorders: a systematic review. Pain Physician. Exercise therapy for chronic musculoskeletal pain: Innovation by altering pain memories.
Epub Jul Is exercise effective for the management of neck pain and associated disorders or whiplash-associated disorders? Spine J. Epub Feb A modern neuroscience approach to chronic spinal pain: combining pain neuroscience education with cognition-targeted motor control training. Phys Ther. How to explain central sensitization to patients with 'unexplained' chronic musculoskeletal pain: practice guidelines.
Epub May National Library of Medicine U. National Institutes of Health U. Department of Health and Human Services. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Behavioral: Modern pain neuroscience approach Behavioral: Usual care evidence-based physiotherapy. Not Applicable. Study Type :. Estimated Enrollment :. Triple Participant, Investigator, Outcomes Assessor. Actual Study Start Date :. Estimated Primary Completion Date :.
Estimated Study Completion Date :. At the Neuroscience Institute, we use a multidisciplinary research approach to study how sensory systems and brain-integrating systems develop, and how sensory inputs are detected and processed by the nervous system in health and disease. We have experienced researchers working on hearing, balance, vision, olfaction, brain-integrating systems and pain.
Research and Discovery at the Neurosciences Center
Our teams bring together expertise in electrophysiology, imaging and computing, combined with sophisticated in vivo models and analysis of human tissues. We have started to bridge the gaps between molecular biology, developmental neurobiology, systems physiology, and behaviour. These advances have important applications to health, particularly for the many people affected by developmental and sensory disorders including nerve injury, hearing loss, chronic pain and autism.
We are also investigating the mechanisms leading to age-related deterioration of sensory function and how this can be prevented. We study development, function and ageing of the vertebrate auditory and vestibular systems. Our current research shows how electrophysiological activity during development shapes the differentiation of mammalian hair cells and reveals subtle interactions in the development of the mechano-electrical transduction machinery and of the ribbon synapses that relay information to the nervous system.
Recent Advances in the Neuroscience of Chronic Pain – Hansma Research Group
This is associated with the exquisite mechanisms for tuning in hair cells and their afferent neurons along the ionotopic gradient. We are exploring the application of cell therapies to repair nerve damage to the inner ear and the study of genetic models of human deafness and balance in mice and zebrafish. Innovative light microscope techniques are also being used to reveal detailed images of the inner ear sensory structures.
Hearing Research Group at the University of Sheffield. We work with fruit fly and zebrafish visual systems, utilising genetic tools, optical imaging, electrophysiology and computational modelling to study visual information processing from photoreceptors to neural networks and animal behaviour. Nociceptive, environmental and neuroendocrine factors determining pain behaviour in animals A. Aloisi, G.
Functional imaging studies of the pain system in man and animals C. Porro, M. Limbic processes and the affective dimension of pain C. Neuropeptides, Inflammation and Neuropathic Injuries. Neurogenic mechanisms and neuropeptides in chronic pain A. Peripheral opioid analgesia - facts and mechanisms A.
Alterations in the functional properties of dorsal root ganglion cells with unmyelinated axons after a chronic nerve constriction in the rat R. LaMotte et al. Plasticity of messenger function in primary afferents following nerve injury - implications for neuropathic pain Z. Wiesenfeld-Hallin, X. The possible role of substance P in eliciting and modulatig deep somatic pain S.
Iowa Neuroscience Institute
Hoheisel, A. Studies of the release of immunoreactive galanin and dynorphin A in the spinal cord of the rat A. Duggan, R.
Neurotransmitters and Plasticity.