The mixture was stirred for 24 h with bubbling carbon dioxide at room temperature, and then filtrated. Excess non-bonded Compound C was washed with acetone overnight after the procedure iii. Elemental analysis: C 8. The surface concentration of cellulose derivative on the CSP-1 was determined to be 6. The columns packed with CSP-1 afforded efficiency of Approximately 3. The t 0 for the analytical column was measured from the retention of sodium nitrate in reversed phase mode and 1,3,5-tri- tert -butylbenzene in normal phase mode.
The void volume was 1. Chiral separations were conducted in normal and reversed-phase mode. Mixtures of hexane and alcohols were used in the enantioseparation. Fourteen analytes were effectively separated, with k 1 ranging from 1. The mechanism of enantioselectivity of polysaccharide derivatives has been studied by several research groups. Fukui et al. The helical backbone and side chain of the cellulose derivative keep the analyte in the chiral cavities environment, so it could be deduced that solutes would be wrapped into the heliced polymer cavity.
However, it afforded Rs up to 1. This may be due to H-bonding and steric effects. In contrast to Compound 14 separated in normal phase mode, Compound 20 was separated in reversed-phase. Compound 14 contained additional phenyl rings while Compound 20 embodied two free phenolic groups. The two free phenyl hydroxyl groups of Compound 20 made H-bonding interaction with mobile phase and CSP-1 possible. Standard sample Compound 3 was separated on different batches of CSP in the same condition. The stability of the immobilized CSP would undoubtedly be a determining factor for the repeatability of separation methods and the column lifetime.
Six hundred injections were carried out in both normal and reversed-phase modes within two months. Owning to its immobilized nature, non-standard solvents were tried to be used as eluents. Additionally, the last process of the preparation of the CSP is to wash the CSP with acetone overnight by soxhlet exaction, aiming at washing off the non-bonded 6-azido-2,3-di p -chlorophenylcarbamoylated cellulose. In summary, a novel chemically immobilized cellulose-based CSP has been prepared using Staudinger reaction between 6-azido-2,3-di p -chlorophenylcarbamoylated cellulose and amino functionalized silica gel.
Chiral compounds were effectively enantioseparated in either normal phase mode or reversed-phase mode. Additionally, results revealed good reproducibility and stability of the CSP. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Sign In. Advanced Search. Article Navigation. Close mobile search navigation Article Navigation.
Volume Article Contents. Materials and Methods. Results and Discussion. Oxford Academic. Google Scholar. Su Qin Wu. Zhi Li Fang. Wei Guang Zhang. Zhen Bin Zhang. Jun Fan.
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Figure 5. Figure 6. Search ADS. Useful chiral packing materials for high performance liquid chromatographic resolution of enantiomers: Phenylcarbamates of polysaccharides coated on silica gel. Controlled chiral recognition of cellulose triphenylcarbamate derivatives as stationary phases for HPLC. Resolution by high performance liquid chromatography using polysaccharide carbamates and benzoates as chiral stationary phases.
Chiral stationary phases for HPLC: Cellulose tris 3,5-dimethylphenylcarbamate and tris 3,5-dichlorophenylcarbamate chemically bonded to silica gel. Covalently bonded polysaccharide derivatives as chiral stationary phases in high performance liquid chromatography. Immobilized polysaccharide derivatives onto silica gel: Facile synthesis of chiral packing materials by means of intermolecular polycondensation of triethoxysilyl groups. Nolan, R. Darcy, and B. Perly, S. Moutard, F. Pilard-francotte, E.
Brandel et al. Armstrong , Derivatized cyclodextrins immobilized on fused-silica capillaries for enantiomeric separations via capillary electrophoresis, gas chromatography, or supercritical fluid chromatography , Analytical Chemistry , vol. Lai, W. Tang, and S. Ng , Novel cyclodextrin chiral stationary phases for high performance liquid chromatography enantioseparation: Effect of cyclodextrin type , Journal of Chromatography A , vol.
Bicchi , New asymmetrical per-substituted cyclodextrins 2-O-methylO-ethyl- and 2-O-ethylO-methylO-t-butyldimethylsilyl-?? Berthod, S. Chang, and D. Armstrong , Empirical procedure that uses molecular structure to predict enantioselectivity of chiral stationary phases , Analytical Chemistry , vol. Wistuba and V. Schurig , Enantiomer separation by pressure-supported electrochromatography using capillaries packed with Chirasil-Dex polymer-coated silica , Electrophoresis , vol.
Schurig , Enantiomer separation by capillary electrochromatography on a cyclodextrin-modified monolith , Electrophoresis , vol. Schurig , Enantiomer separation of chiral pharmaceuticals by capillary electrochromatography , Journal of Chromatography A , vol. Rebscher and U. Pyell , A method for the experimental determination of contributions to band broadening in electrochromatography with packed capillaries , Chromatographia , vol.
Dulay , Automated capillary electrochromatography: reliability and reproducibility studies , Tsuda, T. Knox and I. Grant , Electrochromatography in packed tubes using 1. Schurig, D. Wistuba, V. Hopkins, and J. Li, D. Fries, and A. Malik , Sol???
Enantioseparation of Six Antihistamines with Immobilized Cellulose Chiral Stationary Phase by HPLC
Rathore, E. Wen, and C. Rathore and C. Mayer and V. Schurig , Enantiomer separation by electrochromatography on capillaries coated with chirasil-dex. Mayer, M. Schleimer, and V. Schurig , Dual chiral recognition system involving cyclodextrin derivatives in capillary electrophoresis , Journal of Microcolumn Separations , vol. Schurig , Enantiomer separation using mobile and immobile cyclodextrin derivatives with electromigration , Electrophoresis , vol. Schurig and S. Mayer , Separation of enantiomers by open capillary electrochromatography on polysiloxane-bonded permethyl-??
Francotte and M.
Jung , Enantiomer separation by open-tubular liquid chromatography and electrochromatography in cellulose-coated capillaries , Chromatographia , vol. Tsuda, K. Nomura, and G. Nakagawa , Open-tubular microcapillary liquid chromatography with electro-osmosis flow using a UV detector , Journal of Chromatography A , vol. Liu , Study of physically adsorbed stationary phases for open tubular capillary electrochromatography , Electrophoresis , vol. Liu , Open tubular capillary electrochromatography with adsorbed stationary phase , Analytica Chimica Acta , vol. Geng , Capillary coated with layer-by-layer assembly of?
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Cheong , Comprehensive overview of recent preparation and application trends of various open tubular capillary columns in separation science , Journal of Chromatography A , vol. Pesek and M. Matyska , Electrochromatography in chemically modified etched fused-silica capillaries , Journal of Chromatography A , vol. Pesek, M. Matyska, and S. Cho , Open tubular capillary electrochromatography in etched, chemically modified 20??
Menezes , Chiral separations by open tubular capillary electrokinetic chromatography , Journal of Chromatography A , vol. Matyska , Open tubular capillary electrokinetic chromatography in etched fused-silica tubes , Journal of Chromatography A , vol. Matyska, and R.
Yu , Synthesis and characterization of endcapped C18 stationary phases using a silica hydride intermediate , Journal of Chromatography A , vol. Matyska, and X. Pan , Synthesis and evaluation of a C8 stationary phase on a silica hydride surface by hydrosilation of 1-octyne , Journal of Chromatography A , vol. Velpula , Open tubular capillary electrochromatography migration behavior of enkephalins in etched chemically modified fused silica capillaries , Journal of Chromatography A , vol. Matyska, and M. Moore , Surface acoustic wave chemical microsensors based on covalently bound selfassembled host monolayers , Adv.
Mater , issue. Li and M. Ma , Surface acoustic wave microsensors based on cyclodextrin coatings , Sensors and Actuators B: Chemical , vol. Danel , Evaluation of three neutral capillary coatings for the determination of analytecyclodextrin binding constants by affinity capillary electrophoresis.
Application to N,N? Zhang and Z. Rassi , Enantiomeric separation by capillary electrochromatography II. Chiral separation of dansyl amino acids and phenoxy acid herbicides on sulfonated silica having surface-bound hydroxypropyl-?? Hongjun , Microwave-Assisted Preparation of a?? Foret , Capillary electrophoresis mass spectrometry coupling with immobilized enzyme electrospray capillaries , Journal of Chromatography A , vol. Oliveros , Chiral-bonded silica gel stationary phases obtained from chiral silanes for high-performance liquid chromatography , Journal of Chromatography A , vol.
Lee and G. Si :?? Stewart and J. Sun , Covalently Attached Monolayers on Hydrogen? Zhong and S. Huang, J. Mi, and X. Zhang , Capillary electrochromatography of amino acids with a protein-bonded porous-layer open-tubular column , Journal of Separation Science , vol. Pan , In situ synthesis of homochiral metal??? Fei , Chiral metal???
Zaidi, S. Lee, and W. Cheong , Open tubular capillary columns with basic templates made by the generalized preparation protocol in capillary electrochromatography chiral separation and template structural effects on chiral separation capability , Journal of Chromatography A , vol. Onuska , Preparation of surface-modified wide-bore wall-coated open-tubular columns , Journal of Chromatography A , vol. Dohmeier and J. Jorgenson , Evaluation of etched borosilicate glass capillary columns in reversed phase open tubular liquid chromatography , Journal of Microcolumn Separations , vol.
Zhang, and C. Al-hussin , Preparation and electrochromatographic characterization of new chiral? Chen and K. Chehimi and J. Pinson , Applied surface chemistry of nanomaterials Available from , Khalil , Gold-decorated polymeric monoliths: In-situ vs ex-situ immobilization strategies and flow through catalytic applications towards nitrophenols reduction , Polymer , vol.
Hamer, A. Yone, and I.
Li , Enantioselective open-tubular capillary electrochromatography using cyclodextrinmodified gold nanoparticles as stationary phase , Journal of Chromatography A , issue. Gusev, X. Huang, and C. Tennikova , High-performance membrane chromatography of proteins, a novel method of protein separation , Journal of Chromatography A , vol. Svec , Design of the monolithic polymers used in capillary electrochromatography columns , Journal of Chromatography A , vol.
Ross and R. Liao, and R. Zhang , High-performance liquid chromatography on continuous polymer beds , Journal of Chromatography A , vol. Araya-farias , A new strategy for simultaneous synthesis and efficient anchorage of?? Zhong and Z. Rassi , -glycans , Journal of Separation Science , vol. Cortes , Porous ceramic bed supports for fused silica packed capillary columns used in liquid chromatography , Journal of High Resolution Chromatography , vol. Currivan, D. Connolly, and B.
Paull , Production of polymer monolithic capillary columns with integrated gold nano-particle modified segments for on-capillary extraction , Microchemical Journal , vol. Chen, T. Huang, and X. Zhang , Immunoaffinity extraction of testosterone by antibody immobilized monolithic capillary with on-line laser-induced fluorescence detection , Talanta , vol. Dziomba , Solid supports for extraction and preconcentration of proteins and peptides in microfluidic devices: A review , Analytica Chimica Acta , vol.
Ansell , Molecularly imprinted polymers for the enantioseparation of chiral drugs , Advanced Drug Delivery Reviews , vol. Li , Development and characterization of an immunoaffinity monolith for selective on-line extraction of bisphenol A from environmental water samples , Analytica Chimica Acta , vol. Tanret, D. Mangelings, and Y. Vander-heyden , Influence of the polymerization-mixture composition for monolithic methacrylate-based columns on the electrochromatographic performance of drug molecules , Journal of Pharmaceutical and Biomedical Analysis , vol.
Wistuba , Chiral silica-based monoliths in chromatography and capillary electrochromatography , Journal of Chromatography A , vol. Bragg and S. Shamsi , A novel positively charged achiral co-monomer for?? Zhang , Preparation of a? Gu and S.
Guo , Influence of the linking spacer length and type on the enantioseparation ability of?? Kornysova, P. Owens, and A. Lv , Preparation of novel?? Tian , Novel?? Guerrouache, M. Millot, and B.
Li , Fabrication and evaluation of chiral monolithic column modified by?? Li , Application of cyclodextrin-modified gold nanoparticles in enantioselective monolith capillary electrochromatography , Talanta , vol. Chankvetadze, C. Yamamoto, and Y. Ghanem , Immobilized?? Wistuba, L. Banspach, and V.
Lubda , Monolithic silica columns with chemically bonded? Yuan, Y. Wang, and G. Hoegger and R. Freitag , Acrylamide-based monoliths as robust stationary phases for capillary electrochromatography , Journal of Chromatography A , vol. Gargano , Monoliths with chiral surface functionalization for enantioselective capillary electrochromatography , Journal of Pharmaceutical and Biomedical Analysis , vol. Vegvari , A new easy-to-prepare homogeneous continuous electrochromatographic bed for enantiomer recognition , Electrophoresis , vol.
Ueno , Enantiomeric separations of cationic and neutral compounds by capillary electrochromatography with monolithic chiral stationary phases of?? Wahl, I. Schnell, and U. Pyell , Capillary electrochromatography with polymeric continuous beds synthesized via free radical polymerization in aqueous media using derivatized cyclodextrins as solubilizing agents , Journal of Chromatography A , vol.
Wahl , Synthesis of a polyrotaxane-based macroporous polymer as stationary phase for capillary electrochromatography via host-guest complexation of N,N'-ethylenedianilinediacrylamide with statistically methylated? Sci , issue. Zeng, H. Li, and J. Lin , Chiral separation of dansyl amino acids by PDMS microchip gel monolithic column electrochromatography with?? Kornysova, R. Jarmalaviciene, and A. Hilder, F. Svec, and J. Ostryanina, G. Vlasov, and T. Tennikova , Multifunctional fractionation of polyclonal antibodies by immunoaffinity high-performance monolithic disk chromatography , Journal of Chromatography A , vol.
Jmeian and Z. Liang , Class-specific immunoaffinity monolith for efficient on-line clean-up of pyrethroids followed by high-performance liquid chromatography analysis , Journal of Chromatography B , vol.