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Prerequisites The aim of the course is the contextualization of the previously acquired theoretical knowledge in a highly vocational view which allows an effective competence for an actual job employment. Therefore, according to the Academic Regulation, the cultural prerequisites necessary for the course are primarily the extensive and substantiated knowledge of the major elements of cellular and molecular biology, histology, genetics and genomics, biochemistry, anatomy and physiology.

The skills obtained in these disciplines are essential so that students can understand the concepts of the molecular etiopathology of diseases. Based on these assumptions, the student will be able to draw considerable profit from the training course.

Teaching methods Students receive frontal lectures. Each lesson lasts two hours or four hours and is on a specific subject, relating it to others already exposed, to allow an integrated vision. Students are then invited to conduct seminars about their personal interest. The seminars were held in small groups, in the presence of all the students of the course. For this purpose, the teacher can support students also with materials in english language related to the subject of the seminar, which must be presented using computer support Power Point , and that has the value of teaching implementation and evaluation.

Learning verification modality The evaluation of the student is performed through an oral exam at the end of the course lectures.

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On the basis of the vocational training of the CdLM, the oral exam consists in the preparation of an oral presentation, individually or in a small group maximum persons , on topics included among the molecular basis of diseases. During the presentation, which takes place in the presence of all students and that also has educational value, at the same time, is verified the acquisition of the cultural basis inherent in the course, the ability to integrate informations, to perform an in-depth analysis and the level of professionalism achieved by the learners. Extended program Principles of Immunology -Cells and organs of the immune system functions, interactions and regulation -Immunodeficiencies, hypersensitivity and autoimmune reactions I, II, III.

Mechanisms for recognition of a pathogen. Distinctive characters between acute and chronic inflammation. The plasma and tissue mediators of inflammation. The exudation: different types of exudate.

Manolis Kellis - 1 Understanding the Molecular Basis of Human Disease

The acute phase proteins. The cells of acute inflammation. Diapedesis, the chemotaxis and phagocytosis. The different types of acute inflammation: serous, sero-fibrinous, fibrinous, catarrhal, purulent, hemorrhagic, necrotic-hemorrhagic and allergic. Chronic Inflammation: granulomatous and interstitial.

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Molecular Pathology: The Molecular Basis of Human Disease by William B. Coleman

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Subjects Pathology, Molecular. Cytogenetic Analysis -- methods.

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Molecular Pathology

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Davis, Robin D. Funkhousser Jr. Coleman and Gregory J.