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In: Chemoinformatics Approaches to Virtual Screening. Alexandre Varnek and Alexander Tropsha. Computer-aided predictions for medicinal chemistry via Internet. Computer-aided prediction of QT-prolongation. PASS: Identification of probable targets and mechanisms of toxicity. Prediction of biological activity spectra for organic compounds. Russian Chemical Journal , 50 2 , Computer prediction of biological activity spectra for nitrogen-containing organic compounds.
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International Journal of Biological Macromolecules, , 50 3 , —; doi Al-Rehaily A. Solanopubamine, a rare steroidal alkaloid from Solanum schimperianum : Synthesis of some new alkyl and acyl derivatives, their anticancer and antimicrobial evaluation. Journal of Saudi Chemical Society, , 17 1 , 67—76; doi From in silico target prediction to multi-target drug design: Current databases, methods and applications.
Journal of Proteomics, 74 12 , Nigsch F. Computational methods for early predictive safety assessment from biological and chemical data. Pospieszny T. Synthesis and spectroscopic studies of new bile acid derivatives linked by a 1,2,3-triazole ring. Tetrahedron Letters, 53 3 , Bello C. Anti-cancer activity of 5- O -alkyl 1,4-imino-1,4-dideoxyribitols. Liu P. Di Giorgio C. Food and Chemical Toxicology, 49 11 , Chand B. O'Boyle N.
Open Babel: An open chemical toolbox. Chemistry Cenral, 3 1 , Liaras K. Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. Dhanachandra Singh Kh. Journal of Molecular Graphics and Modelling, 30, Zydek G. Normal and reversed phase thin layer chromatography data in quantitative structure—activity relationship study of compounds with affinity for serotonin 5-HT receptors.
Journal of Chromatography B, 20 , Verbitskiy E. Reactions of 5- het arylethyl-2 1h -pyrazinones with terminal arylacetylenes promoted by microwave radiation. Chemistry of Heterocyclic Compounds, 47 6 , Khurana N. PASS assisted prediction and pharmacological evaluation of novel nicotinic analogs for nootropic activity in mice. Ursu O. Understanding drug-likeness. Wiley Interdiscip. Saidemberg D. Chemometric analysis of Hymenoptera toxins and defensins: A model for predicting the biological activity of novel peptides from venoms and hemolymph.
Peptides, 32 9 , Singh Kh. Basanagouda M. Indian Journal of Pharmaceutical Sciences, 73 1 , Data governance in predictive toxicology: A review. Vasilevsky S. Rapid access to new bioconjugates of betulonic acid via click chemistry. Samwald M. Linked open drug data for pharmaceutical research and development. Willighagen E. Resource description framework technologies in chemistry. Panico A. Heteroaryliminothiazolidinones as inhibitors of cartilage degradation. Bioorganic Chemistry, 39 1 , Ghadimi S. Iran Chem. Bieler M. Chem Inf. Potikha L.
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European Journal of Medicinal Chemistry , 46 1 , Normal and reversed phase thin layer chromatography data in quantitative structure-activity relationship study of compounds with affinity for serotonin 5-HT receptors. Taboureau O. High Throughput Screen. Tian R.
Acta Phys. Navarrete-Vazquez G. Mashentseva A. Synthesis and biological activity of the pinostrobin oxime complex compounds with some d-metals. Sapa J. Antiarrhythmic and antioxidant activity of novel pyrrolidinone derivatives with adrenolytic properties. Naunyn-Schmiedebergs Arch. Condensed Isoquinolines. Xie X. Exploiting PubChem for virtual screening. Drug Discov. Agadzhanyan V. Targeted search for a lead compound in a series of cinnamic acid derivatives possessing antiradical activity. Jimenez-Romero C.
Kulakov I. Synthesis and crystal structure of 5-methyl n-anabasinyl -5,6-dihydro-1,3-thiazinone from the alkaloid anabasine. A practical synthesis and spectroscopic study of new potentially biologically active S-lithocholic acid-substituted derivatives of 2-thiouracil. Tetrahedron Lett. Model-Free Drug-Likeness from Fragments. Zhao J. Molecular networks for the study of TCM Pharmacology. Fjodorova N. Quantitative and qualitative models for carcinogenicity prediction for non-congeneric chemicals using CP ANN method for regulatory uses. Bartkowiak G. Phosphorus Sulfur Silicon Relat. Merlot C. Computational toxicology - a tool for early safety evaluation.
Drug Discovery Today , 15 , A practical synthesis and spectroscopic study of new potentially biologically active S -lithocholic acid-substituted derivatives of 2-thiouracil. Tetrahedron Letters , 51 32 , In silico biological activity evaluation of some 3-substitutedhydroxymethyl-2Hpyranones. Journal of Pharmacy Research , 3 10 : Ferdosiyan M. In silico design and selection of anti-fungal AmB-polyene-analog lead molecules by virtual screening method.