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HPG Axis’ Role in Female Reproduction and Development

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In women, a lack of luteinising hormone means that ovulation does not occur and menstrual periods may not occur regularly. An example of a condition which can be caused by too little luteinising hormone is amenorrhoea. About Contact Events News.

Hypothalamus-Pituitary-Gonad Axis

Search Search. You and Your Hormones. Students Teachers Patients Browse. Human body. Home Hormones Luteinising hormone. Luteinising hormone Luteinising hormone is produced by the pituitary gland and is one of the main hormones that control the reproductive system. Glossary All Hormones Resources for Hormones.

ABBREVIATIONS

Alternative names for luteinising hormone Interstitial cell stimulating hormone; luteinizing hormone; lutropin; LH What is luteinising hormone? How is luteinising hormone controlled? What happens if I have too much luteinising hormone?

Hormonal Control of the Hypothalamo-Pituitary-Gonadal Axis | SpringerLink

What happens if I have too little luteinising hormone? Last reviewed: Feb Prev. Melanocyte-stimulating hormone. Once FSH is released into the bloodstream, it binds to sustentacular cells, specifically the Sertoli cells. These cells release a protein called androgen-binding protein, which increases the concentration of testosterone to allow for spermatogenesis.

Once testosterone is produced and secreted via LH binding with the interstitial cells, it binds with androgen-binding protein to maintain spermatogenesis. Too much testosterone will lead to the hormone having a negative-feedback effect on the hypothalamus. Inhibin also has a negative-feedback effect on the hypothalamus.

Inhibin has an indirect effect in which it inhibits the hypothalamus via inhibiting activin. The hormones produced by the HPG axis also contribute to secondary sex characteristics in males. These include, but are not limited to, body hair growth, facial hair growth, increased muscle mass, deepened voice, and greater shoulder width.

Molecular aspects of the ontogeny of the pituitary-gonadal axis

Millar, R. Gonadotropin-releasing hormone receptors. Endocrine Reviews , 25, Peper, J. HPG-axis hormones during puberty: A study on the association with hypothalamic and pituitary volumes. Psychoneuroendocrinology , 35 1 ,

The hypothalamus and pituitary gland - Endocrine system physiology - NCLEX-RN - Khan Academy